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NLRP3 inflammasome priming: A riddle wrapped in a mystery inside an enigma - McKee - 2020 - Journal of Leukocyte Biology - Wiley Online Library
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NLRP3-associated autoinflammatory diseases: Phenotypic and molecular characteristics of germline versus somatic mutations - ScienceDirect
PKD-mediated NLRP3 activation pathway and the relevant CAPS mutations.... | Download Scientific Diagram
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Nlrp3 inflammasome activation in macrophages suffices for inducing autoinflammation in mice | EMBO reports
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Cryo-sensitive aggregation triggers NLRP3 inflammasome assembly in cryopyrin-associated periodic syndrome | eLife
PKA-mediated NLRP3 inhibition pathway and the relevant CAPS mutations.... | Download Scientific Diagram
![INFLAMMASOME INHIBITORS - 21st Century Miracle Drugs: Spotlight on Clinical NLRP3 Inflammasome Inhibitors INFLAMMASOME INHIBITORS - 21st Century Miracle Drugs: Spotlight on Clinical NLRP3 Inflammasome Inhibitors](https://drug-dev.com/wp-content/uploads/2023/04/F1-5.jpg)
INFLAMMASOME INHIBITORS - 21st Century Miracle Drugs: Spotlight on Clinical NLRP3 Inflammasome Inhibitors
![Cryo-sensitive aggregation triggers NLRP3 inflammasome assembly in cryopyrin-associated periodic syndrome | eLife Cryo-sensitive aggregation triggers NLRP3 inflammasome assembly in cryopyrin-associated periodic syndrome | eLife](https://iiif.elifesciences.org/lax/75166%2Felife-75166-fig2-figsupp1-v2.tif/full/full/0/default.jpg)
Cryo-sensitive aggregation triggers NLRP3 inflammasome assembly in cryopyrin-associated periodic syndrome | eLife
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Cryo-sensitive aggregation triggers NLRP3 inflammasome assembly in cryopyrin-associated periodic syndrome | eLife
![Waggoner Lab on X: "Cryopyrin-associated periodic syndrome (CAPS) NLRP3 variants form constitutively active inflammasomes inducing pyroptosis & IL-18 release without cell priming, contributing to autoinflammatory flares while metabolically limiting IL ... Waggoner Lab on X: "Cryopyrin-associated periodic syndrome (CAPS) NLRP3 variants form constitutively active inflammasomes inducing pyroptosis & IL-18 release without cell priming, contributing to autoinflammatory flares while metabolically limiting IL ...](https://pbs.twimg.com/media/GFqlwEtXUAAbYzb.png)
Waggoner Lab on X: "Cryopyrin-associated periodic syndrome (CAPS) NLRP3 variants form constitutively active inflammasomes inducing pyroptosis & IL-18 release without cell priming, contributing to autoinflammatory flares while metabolically limiting IL ...
The NLRP3/NEK7 complex domains and related CAPS mutations. A 3D cartoon... | Download Scientific Diagram
![The NLRP3 inflammasome: contributions to inflammation-related diseases | Cellular & Molecular Biology Letters | Full Text The NLRP3 inflammasome: contributions to inflammation-related diseases | Cellular & Molecular Biology Letters | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs11658-023-00462-9/MediaObjects/11658_2023_462_Fig1_HTML.png)
The NLRP3 inflammasome: contributions to inflammation-related diseases | Cellular & Molecular Biology Letters | Full Text
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The NLRP3 inflammasome: molecular activation and regulation to therapeutics | Nature Reviews Immunology
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Pathogenic variants in the NLRP3 LRR domain at position 861 are responsible for a boost-dependent atypical CAPS phenotype - Journal of Allergy and Clinical Immunology
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Pathogenic NLRP3 mutants form constitutively active inflammasomes resulting in immune-metabolic limitation of IL-1β production | Nature Communications
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